Pharmacologic Substance
fondaparinux sodium
[ fon-duh-payr-ih-nux soh-dee-um ]
Effect:
Decreased Coagulation Factor Activity
May Prevent:
Postoperative Complications; Thromboembolism; Venous Thrombosis
May Treat:
Pulmonary Embolism;
Venous Thrombosis
More Information:
Definitions related to fondaparinux sodium:
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A drug used to prevent blood clots from forming inside blood vessels in the leg. It is being studied in the prevention of blood clots in some cancer patients, including women having surgery for cancer of the reproductive tract. It is a type of anticoagulant.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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The sodium salt form of fondaparinux, a synthetic glucopyranoside with antithrombotic activity. Fondaparinux sodium selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. (NCI05)NCI ThesaurusU.S. National Cancer Institute, 2021
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