Pharmacologic Substance
ganglioside
gan·gli·o·side [ gang-glee-uh-sahyd ]
Subclass of:
Acidic Glycosphingolipids
Definitions related to gangliosides:
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A complex molecule that contains both lipids (fats) and carbohydrates (sugars) and is found in the plasma (outer) membrane of many kinds of cells. Several different types of gangliosides have been identified.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Sialoglycosphingolipids (synonym: gangliosides) are glycosphingolipids carrying one or more sialic residues. Sialic acid is the generic term for N-acetyl- or N-glycoloylneuraminic acid. Gangliosides are named as N-acetyl- (or N-glycoloyl-)neuraminosyl-(X)osylceramide, where (X) stands for the root name of the neutral oligosaccharide to which the sialosyl residue is attached; found principally in nerve tissue, spleen, and thymus; GM1 accumulates in generalized gangliosidosis; GM2 accumulates in Tay-Sachs disease.NCI ThesaurusU.S. National Cancer Institute, 2021
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Subclass of acidic glycosphingolipids containing one or more sialic acid residues.CRISP ThesaurusNational Institutes of Health, 2006
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A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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