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globozoospermia
Definitions related to globozoospermia:
  • A rare but severe cause of male infertility. It is characterized by the presence of 100% round headed spermatozoa and lack of acrosomes.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Any structural anomaly of the acrosome resulting in a round sperm head.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • Globozoospermia is a rare form of male infertility. Men affected by this condition have abnormal sperm with a round (rather than oval) head and no acrosome (a cap-like covering which contains enzymes that break down the outer membrane of an egg cell). As a result of these abnormalities, the sperm are unable to fertilize an egg cell,...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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