Enzyme
glutamate decarboxylase
glu·ta·mate de·car·box·yl·ase
Definitions related to glutamate decarboxylase:
  • A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • (glutamic acid decarboxylase) A protein found in beta cells, the cells that create insulin.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
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