Pharmacologic Substance
glutathione disulfide
glu·ta·thi·one di·sul·fide
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to glutathione disulfide:
  • (oxiglutatione) The oxidized disulfide form of glutathione (GSH) with potential protective activity. Glutathione disulfide (GSSG) is reduced by glutathione reductase to GSH. GSSG and GSH together play important roles in numerous redox reactions, such as those involved in the detoxification of harmful substances and free radicals, and in reactions preventing oxidative damage in erythrocytes. Upon ocular administration in irrigation solution, glutathione disulfide may exert a beneficial effect on the intracellular redox state of glutathione, thereby protecting the integrity and barrier function of the corneal endothelial cells.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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