Pharmacologic Substance
granisetron Audio
[ gra-nih-seh-tron ]
Brand Names:
Sancuso; Sustol
Effect:
Decreased Serotonin Activity; Emesis Suppression
May Prevent:
Postoperative Nausea and Vomiting
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to granisetron:
  • A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Granisetron is a type of serotonin receptor antagonist and a type of antiemetic.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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