Enzyme
guanylate cyclase
Definitions related to guanylate cyclase:
  • An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are receptors for hormones, and intracellular soluble GCs that are activated by the gaseous second messenger nitric oxide (NO). EC 4.6.1.2
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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