Pharmacologic Substance
haloperidol
hal·o·per·i·dol [ hal-oh-per-i-dawl, -dol ]
Brand Names:
Haldol
Effect:
Decreased Brain Stem Organized Electrical Activity; Decreased Dopamine Activity; Hypothalamic Endocrine Activity Alteration
May Treat:
Child Behavior Disorders;
Psychotic Disorders;
Schizophrenia;
Substance Withdrawal Syndrome;
Tourette Syndrome;
Vomiting
More Information:
Definitions related to haloperidol:
-
A drug used to treat certain mental and neurological disorders. It is also being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of antiemetic and a type of antipsychotic.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity.NCI ThesaurusU.S. National Cancer Institute, 2021
-
A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
USP lists as an antipsychotic and as an "antidyskinetic" used in Tourette syndrome.CRISP ThesaurusNational Institutes of Health, 2006
Return to OpenMD Medical Dictionary
> H
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.