Virus
human papillomavirus
hu·man pap·il·lo·ma·vi·rus [ hyoo-mun pa-pih-loh-muh-vy-rus ]
Also called:
HPV
Definitions related to human papillomavirus:
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(hpv) Human papillomavirus (HPV) is a group of related viruses. They can cause warts on different parts of your body. There are more than 200 types. About 40 of them are spread through direct sexual contact with someone who has the virus. They can also spread through other intimate, skin-to-skin contact. Some of these types can cause cancer. There are two categories of sexually transmitted HPV. Low-risk HPV can cause warts on or around your genitals, anus, mouth, or throat. High-risk HPV can cause various cancers: Cervical cancer; Anal cancer; Some types of oral and throat cancer; Vulvar cancer; Vaginal cancer; Penile cancer. Most HPV infections go away on their own and don't cause cancer. But sometimes the infections last longer. When a high-risk HPV infection lasts for many years, it can lead to cell changes. If these changes are not treated, they may get worse over time and become cancer. HPV infections are very common. Nearly all sexually active people are infected with HPV soon after they become sexually active. Some people develop warts from certain low-risk HPV infections, but the other types (including the high-risk types) have no symptoms. If a high-risk HPV infection lasts for many years and causes cell changes, you may have symptoms. You may also have symptoms if those cell changes develop into cancer. Which symptoms you have depends on which part of the body is affected. Health care providers can usually diagnose warts by looking at them. For women, there are cervical cancer screening tests which can find changes in the cervix that might lead to cancer. As part of the screening, women may have Pap tests, HPV tests, or both. An HPV infection itself cannot be treated. There are medicines that you can apply to a wart. If they don't work, your health care provide could freeze, burn, or surgically remove it. There are treatments for the cell changes caused by infection with high-risk HPV. They include medicines that you apply to the area that is affected and various surgical procedures. People who have HPV-related cancers usually get the same types of treatment as people who have cancers that are not caused by HPV. An exception to this is for people who have certain oral and throat cancers. They may have different treatment options. Correct usage of latex condoms greatly reduces, but does not completely eliminate, the risk of catching or spreading HPV. If your or your partner is allergic to latex, you can use polyurethane condoms. The most reliable way to avoid infection is to not have anal, vaginal, or oral sex. Vaccines can protect against several types of HPV, including some that can cause cancer. The vaccines provide the most protection when people get them before they are exposed to the virus. This means that it is best for people to get them before they become sexually active. NIH: National Cancer InstituteMedlinePlusU.S. National Library of Medicine, 2025
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A strain of papillomavirus that can infect the skin and mucous membranes of humans.NCIU.S. National Cancer Institute, 2021
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A type of virus that can cause abnormal tissue growth (for example, warts) and other changes to cells. Infection for a long time with certain types of human papillomavirus can cause cervical cancer. Human papillomavirus may also play a role in some other types of cancer, such as anal, vaginal, vulvar, penile, oropharyngeal, and squamous cell skin cancers.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Any viral organism in humans that can be assigned to the family Papillomaviridae.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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Species of papillomavirus causing warts in humans; these benign, squamous epithelial neoplasms can sometimes progress to malignancy.CRISP ThesaurusNational Institutes of Health, 2006
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(human papillomavirus viruses) A large group of viruses that cause HUMAN PAPILLOMAVIRUS INFECTION, e.g., GENITAL WARTS and cancer of the CERVIX; VAGINA; VULVA; ANUS; or OROPHARYNX. Most common clinically important human papilloma viruses are taxonomically members of ALPHAPAPILLOMAVIRUS and GAMMAPAPILLOMAVIRUS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2025
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Human papillomavirus (HPV) produces epithelial tumors of the skin and mucous membranes. The current classification system for HPV, which is based on similarities in genomic sequences, generally correlates with the 3 clinical categories applied to HPV infection: Anogenital or mucosal (further subclassified as latent [asymptomatic],...WebMD, 2025
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