Pathologic Function
hypertrophy Audio
hy·per·tro·phy [ hahy-pur-truh-fee ]
Subclass of:
Pathological Conditions, Anatomical
Etymology:
Greek hyper = above or excessive + trophe = nourishment
Trophe in this case a reference to enlargement.
Definitions related to hypertrophy:
  • Abnormal enlargement of a body part or organ.
    NCI
    U.S. National Cancer Institute, 2021
  • Cell size enlargement due to the increase in the amount of cytoplasm and its constituent organelles. The cells are larger but otherwise the appearance is unchanged.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.