Disease or Syndrome
hypogammaglobulinemia
[ hy-poh-ga-muh-glah-byoo-lih-nee-mee-uh ]
Definitions related to hypogammaglobulinemia:
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A condition in which the level of immunoglobulins (antibodies) in the blood is low and the risk of infection is high.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes.NCI ThesaurusU.S. National Cancer Institute, 2021
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Condition characterized by abnormally low levels of all classes of gamma globulins in the blood.CRISP ThesaurusNational Institutes of Health, 2006
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Hypogammaglobulinemia refers to a set of clinicolaboratory entities with varied causes and manifestations. Several codes in the International Classification of Diseases, 9th edition (ICD-9) relate to disorders in which hypogammaglobulinemia is a primary feature.WebMD, 2019
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Hypogammaglobulinemia occurs when serum immunoglobulin levels are reduced. This occurs due to a variety of underlying primary/congenital intrinsic immune system defects (e.g., common variable immunodeficiency) and secondary immunodeficient states (e.g., medication-related, hematologic malignancy, protein-losing diseases). The most...Athenahealth, Inc., 2019
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