(immunomodulation) Change in the body's immune system, caused by agents that activate or suppress its function.

Physiologic control of immune function. Includes all levels of regulation from gene expression mechanisms, through cell-cell interactions, to organism-wide responses.

Various processes by which antibodies may regulate immune responses; at a simple level, secreted antibody neutralizes the antigen with which it reacts thus preventing further antigenic stimulation of the antibody producing clone; at a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases and perhaps further anti-idiotype antibodies against them; this is the major concept of the immunological network theory.