• A health problem or disease that is identified as likely to be benefited by a therapy being studied in clinical trials. NOTE: Where such a benefit has been established and approved by regulatory authorities, the therapy is said to be approved for such an indication.
  CDISC Terminology
  Clinical Data Interchange Standards Consortium (CDISC), 2021
• A sign, signal, circumstance, or symptom which serves to indicate or point out the cause, pathology, treatment, or issue of an attack of disease; the basis for initiation of a treatment for a disease or of a diagnostic test (causal, or symptomatic, or disease-specific indication).
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• In medicine, a sign, symptom, or medical condition that leads to the recommendation of a treatment, test, or procedure.
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• (indication for use) A general description of the disease or condition the product will diagnose, treat, prevent, cure, or mitigate.
  CDISC Terminology
  Clinical Data Interchange Standards Consortium (CDISC), 2021