Disease or Syndrome
Laron syndrome
Subclass of:
Dwarfism
Definitions related to laron syndrome:
  • An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Growth hormone insensitivity syndrome caused by mutation(s) and/or deletion(s) in the GHR gene, encoding the growth hormone receptor.
    NCI
    U.S. National Cancer Institute, 2021
  • Laron syndrome is a condition that occurs when the body is unable to utilize growth hormone. It is primarily characterized by short stature. Other signs and symptoms vary but may include reduced muscle strength and endurance; hypoglycemia in infancy; delayed puberty; short limbs (arms and legs); and obesity. It is often caused by changes...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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