Laboratory Procedure
laser capture microdissection
Subclass of:
Microdissection
Definitions related to laser capture microdissection:
  • A high-resolution method used to isolate cells from their surrounding tissues, with the aid of a laser beam, under direct microscopic visualization. Specific cells can be isolated directly by cutting target cells away from unwanted cells, to obtain enriched cell populations.
    NCI
    U.S. National Cancer Institute, 2021
  • A technique used for the highly specific and selective capture and isolation of a cell population from a heterogeneous tissue section, cytological preparation, or live cell culture. This technique uses direct visualization of the cells via microscopy as well as a laser energy source for cutting and extraction of the cells.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • Method for procuring pure cells from specific microscopic regions of tissue sections; laser beam focally activates a special transfer film which bonds specifically to cells identified and targeted by microscopy within the tissue section, when the film is removed, the chosen cells are tightly held within the focally expanded polymer for microdissection.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Techniques using a laser to cut away and harvest a specific cell or cluster of cells from a tissue section while viewing it under the microscope.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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