Pharmacologic Substance
lenograstim
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Definitions related to lenograstim:
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A glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions.NCI ThesaurusU.S. National Cancer Institute, 2021
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A recombinant granulocyte colony-stimulating factor that is used to treat or prevent NEUTROPENIA in patients receiving myelosuppressive cancer chemotherapy, for the preparation and collection of blood progenitor cells in PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; and in the treatment of severe congenital neutropenia. Component 1 and Component 2 differ by absence or presence of Neu5Ac in 2-6 linkage to GalNAc side chain.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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