Disease or Syndrome
limbic encephalitis
lim·bic en·ceph·a·li·tis
Subclass of:
Paraneoplastic Syndromes, Nervous System; Central Nervous System Viral Diseases; Encephalitis
Definitions related to limbic encephalitis:
  • A paraneoplastic syndrome marked by degeneration of neurons in the LIMBIC SYSTEM. Clinical features include HALLUCINATIONS, loss of EPISODIC MEMORY; ANOSMIA; AGEUSIA; TEMPORAL LOBE EPILEPSY; DEMENTIA; and affective disturbance (depression). Circulating anti-neuronal antibodies (e.g., anti-Hu; anti-Yo; anti-Ri; and anti-Ma2) and small cell lung carcinomas or testicular carcinoma are frequently associated with this syndrome.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A rare disorder characterized by degenerative changes in the limbic area of the brain. Causes include infections and autoimmune conditions; it may also manifest as a paraneoplastic syndrome, most often caused by small cell lung carcinoma. Signs and symptoms include behavioral changes, hallucinations and dementia.
    NCI
    U.S. National Cancer Institute, 2021
  • Limbic encephalitis represents a group of autoimmune conditions characterized by inflammation of the limbic system and other parts of the brain. The cardinal sign of limbic encephalitis is a severe impairment of short-term memory; however, symptoms may also include confusion, psychiatric symptoms, and seizures. The symptoms typically...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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