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Related terms:
glomerulonephritis
IGA nephropathy
focal glomerulosclerosis
Disease or Syndrome
lupus nephritis
lu·pus ne·phri·tis [ loo-puhs nuh-frahy-tis ]
Subclass of:
Lupus Erythematosus, Systemic; Glomerulonephritis
Definitions related to lupus nephritis:
  • Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Lupus nephritis is a type of glomerulonephritis that constitutes one of the most severe organ manifestations of systemic lupus erythematosus. Lupus nephritis is subclassified in six distinct classes, that represent different manifestations and severities of renal involvement and guide the therapeutic management.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • (lupus glomerulonephritis) Glomerulonephritis in the context of systemic lupus erythematosus.
    NCI
    U.S. National Cancer Institute, 2021
  • Lupus nephritis is glomerulonephritis caused by systemic lupus erythematosus (SLE). Clinical findings include hematuria, nephrotic-range proteinuria, and, in advanced stages, azotemia. Diagnosis is based on renal biopsy. Treatment is of the underlying disorder and usually involves corticosteroids and cytotoxic or other immunosuppressant...
    Merck Manuals
    Merck & Co., Inc., 2025
  • Lupus nephritis, one of the most serious manifestations of systemic lupus erythematosus (SLE), usually arises within 5 years of diagnosis; however, renal failure rarely occurs before American College of Rheumatology criteria for classification are met. Lupus nephritis is histologically evident in most patients with SLE, even those...
    Medscape
    WebMD, 2025
  • Lupus nephritis is a frequent complication in people who have systemic lupus erythematosus - more commonly known as lupus.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Lupus nephritis is a kidney disorder that is a complication of systemic lupus erythematous (SLE), commonly known as lupus. The symptoms of lupus nephritis include blood in the urine, a foamy appearance to the urine, high blood pressure, and swelling in any part of the body. This condition typically occurs in people aged 20 to 40 years....
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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