Sign or Symptom
malaise Audio
ma·laise [ ma-leyz, -muh- ]
Etymology:
Old French mal = bad or ill + aise = ease
This word appeared in English in 1768.
Definitions related to malaise:
  • A feeling of general discomfort or uneasiness, an out-of-sorts feeling.
    NCI
    U.S. National Cancer Institute, 2021
  • A feeling of general discomfort, weakness, or lack of health.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • A general feeling of illness that can be a sign of disease.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A nonspecific feeling of bodily discomfort, fatigue and/or unease.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling.
    Common Terminology Criteria for Adverse Events
    U.S. National Institutes of Health, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.