Immunologic Factor
matuzumab
Definitions related to matuzumab:
  • A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and inhibiting receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation.
    NCI
    U.S. National Cancer Institute, 2021
  • A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. EMD 72000 binds to the epithelial growth factor receptor (EGFR) on tumor cells and blocks growth signals.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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