Pharmacologic Substance
mazindol
Effect:
Bronchodilation; Increased Cerebral Cortex Dopamine Activity; Increased Cerebral Cortex Norepinephrine Activity
May Treat:
Muscular Dystrophy, Duchenne;
Obesity
Definitions related to mazindol:
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5-(p-chlorophenyl)-2,5-dihydro-3H- imidazo(2,1-a)isoindol-5-ol; mimics cocaine and amphetamines by inhibiting catecholamine uptake in CNS synapses, but is not reinforcing or abused; used as a molecular probe and to reduce cocaine craving.CRISP ThesaurusNational Institutes of Health, 2006
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Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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