Disease or Syndrome
megaloblastic anemia
[ meg-uh-luh-blas-tik uh-nee-mee-uh ]
Subclass of:
Anemia, Macrocytic
Definitions related to anemia, megaloblastic:
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(megaloblastic anemia) A disorder characterized by low red blood cells and/or hemoglobin and abnormally large, immature circulating red blood cells.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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(megaloblastic anemia) Anemia characterized by the presence of erythroblasts that are larger than normal (megaloblasts).Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(megaloblastic anemia) Anemia characterized by the presence of unusually large erythroblasts in the bone marrow called megaloblasts. It is usually caused by vitamin B12 or folic acid deficiency. Other causes include toxins and drugs.NCI ThesaurusU.S. National Cancer Institute, 2021
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(megaloblastic anemia) Anemias associated with impaired DNA synthesis in bone marrow progenitor cells leading to odd shaped, macrocytic, or dysfunctional erythrocytes; usually caused by B12 or folate deficiency.CRISP ThesaurusNational Institutes of Health, 2006
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(megaloblastic anemia) Fewer than normal healthy red blood cells in circulation, caused by a lack of folate or vitamin B12. Red cells become large and deformed, and are unable to carry oxygen efficiently.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Megaloblastosis describes a heterogeneous group of disorders that share common morphologic characteristics: large cells with an arrest in nuclear maturation. Nuclear maturation is immature relative to cytoplasmic maturity.WebMD, 2019
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