Pharmacologic Substance
modafinil Audio
[ moh-da-fih-nil ]
Brand Names:
Provigil
Effect:
Increased CNS Organized Electrical Activity; Increased Sympathetic Activity
May Treat:
Attention Deficit Disorder with Hyperactivity; Fatigue; Narcolepsy; Sleep Apnea, Obstructive
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to modafinil:
  • A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.