(mononeuropathy) A focal lesion of a single peripheral nerve. Damage to a sensory nerve is accompanied by sensory impairment of all modalities in the affected anatomic distribution.

Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ISCHEMIA; traumatic injury; compression; CONNECTIVE TISSUE DISEASES; CUMULATIVE TRAUMA DISORDERS; and other conditions.

Single mononeuropathies are characterized by sensory disturbances and weakness in the distribution of the affected peripheral nerve. Diagnosis is clinical but may require confirmation with electrodiagnostic tests. Treatment is directed at the cause, sometimes with splinting, nonsteroidal anti-inflammatory drugs, corticosteroid...