Sign or Symptom
muscle weakness
mus·cle weak·ness [ muhs-uhl week-nis ]
Subclass of:
Neuromuscular Manifestations; Pathologic Processes; Myopathy
Definitions related to muscle weakness:
  • A reduction in the strength of one or more muscles.
    NCI
    U.S. National Cancer Institute, 2021
  • A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Diminished strength in a muscle.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • Reduced strength of muscles.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.