Pharmacologic Substance
nateglinide
[ nuh-teg-luh-nahyd ]
Brand Names:
Starlix
Effect:
Increased Insulin Secretion
May Treat:
Diabetes Mellitus, Type 2
More Information:
Definitions related to nateglinide:
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A phenylalanine and cyclohexane derivative that acts as a hypoglycemic agent by stimulating the release of insulin from the pancreas. It is used in the treatment of TYPE 2 DIABETES.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A phenylalanine derivative of the meglitinide class of agents with hypoglycemic activity. Nateglinide, compared to repaglitinide, binds with a higher affinity to the SUR1 subunit and with a faster onset of action and a shorter duration of action. This agent is metabolized by the cytochrome P450 isoenzyme CYP2C9, and, to a lesser extent, by CYP3A4. The parent drug and metabolites are mainly excreted in the urine and its half-life is about 1.5 hours.NCI ThesaurusU.S. National Cancer Institute, 2021
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