• A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• An uncommon inflammatory skin condition, often associated with diabetes mellitus, that is characterized by the formation of multiple shiny atrophic lesions thought to be due to collagen degeneration with a granulomatous response, thickening of blood vessel walls, and fat deposition. The lesions are usually found on the leg.
  NCI
  U.S. National Cancer Institute, 2021
• Necrobiosis lipoidica is a disorder of collagen degeneration with a granulomatous response, thickening of blood vessel walls, and fat deposition. The main complication of the disease is ulceration, usually occurring after trauma.
  Medscape
  WebMD, 2025
• Necrobiosis lipoidica is a rare skin disorder of collagen degeneration. It is characterized by a rash that occurs on the lower legs. It is more common in women, and there are usually several spots. They are slightly raised shiny red-brown patches. The centers are often yellowish and may develop open sores that are slow to heal....
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences