Cell or Molecular Dysfunction
nonsense mutation
non·sense mu·ta·tion
Definitions related to nonsense mutation:
  • A mutation that alters the genetic code in a way that causes the premature termination of a protein. The altered protein may be partially or completely inactivated, resulting in a change or loss of protein function.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein.
    NCI
    U.S. National Cancer Institute, 2021
  • (mutation, nonsense) A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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