Cell or Molecular Dysfunction
nonsense mutation
non·sense mu·ta·tion
Definitions related to nonsense mutation:
-
A mutation that alters the genetic code in a way that causes the premature termination of a protein. The altered protein may be partially or completely inactivated, resulting in a change or loss of protein function.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein.NCI ThesaurusU.S. National Cancer Institute, 2021
-
(mutation, nonsense) A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> N
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.