Disease or Syndrome
olivopontocerebellar atrophy
Subclass of:
Spinocerebellar Degeneration;
Multiple System Atrophy
Definitions related to olivopontocerebellar atrophies:
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(olivopontocerebellar atrophy) A group of sporadic and inherited neurodegenerative disorders affecting the cerebellum, pons, and inferior olives.NCI ThesaurusU.S. National Cancer Institute, 2021
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(olivopontocerebellar atrophy) Neuronal degeneration in the cerebellum, pontine nuclei, and inferior olivary nucleus.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A group of inherited and sporadic disorders which share progressive ataxia in combination with atrophy of the CEREBELLUM; PONS; and inferior olivary nuclei. Additional clinical features may include MUSCLE RIGIDITY; NYSTAGMUS, PATHOLOGIC; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; and OPHTHALMOPLEGIA. The familial form has an earlier onset (second decade) and may feature spinal cord atrophy. The sporadic form tends to present in the fifth or sixth decade, and is considered a clinical subtype of MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Olivopontocerebellar atrophy (OPCA) is a neurodegenerative syndrome characterized by prominent cerebellar and extrapyramidal signs, dysarthria, and dysphagia. Those who study OPCA quickly learn that it is not a single entity, and that its nosology can be confusing.WebMD, 2019
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Olivopontocerebellar atrophy (OPCA) is a term used for a progressive condition characterized by the degeneration of nerve cells (neurons) in specific areas of the brain. OPCA can be viewed as a finding of several diseases, and indicates a form of progressive ataxia (abnormal or uncontrolled movements) distinguished by characteristic...National Center for Advancing Translational Sciences
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