Biologically Active Substance
omega-n-methylarginine
o·me·ga·n·methylarginine
Subclass of:
Arginine
Definitions related to omega-n-methylarginine:
  • (tilarginine) A pan-nitric oxide synthase (NOS) inhibitor, with potential immunomodulating and antineoplastic activities. Upon administration, tilarginine binds to and inhibits NOS, a free radical signaling molecule that promotes angiogenesis, metastasis, and immunosuppression in the tumor microenvironment (TME). Reduction in NOS activity may abrogate the immunosuppressive TME, enhance tumor antigen-specific immune response and inhibit tumor cell proliferation.
    NCI
    U.S. National Cancer Institute, 2021
  • A competitive inhibitor of nitric oxide synthetase.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (ng-monomethyl-l-arginine) An amino acid derivative used to counteract high blood pressure caused by interleukin-2.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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