Biologically Active Substance
omega-n-methylarginine
o·me·ga·n·methylarginine
Subclass of:
Arginine
Definitions related to omega-n-methylarginine:
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(tilarginine) A pan-nitric oxide synthase (NOS) inhibitor, with potential immunomodulating and antineoplastic activities. Upon administration, tilarginine binds to and inhibits NOS, a free radical signaling molecule that promotes angiogenesis, metastasis, and immunosuppression in the tumor microenvironment (TME). Reduction in NOS activity may abrogate the immunosuppressive TME, enhance tumor antigen-specific immune response and inhibit tumor cell proliferation.NCI ThesaurusU.S. National Cancer Institute, 2021
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A competitive inhibitor of nitric oxide synthetase.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(ng-monomethyl-l-arginine) An amino acid derivative used to counteract high blood pressure caused by interleukin-2.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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