Virus
oncolytic viruses
Subclass of:
Virus
Definitions related to oncolytic viruses:
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(oncolytic virus) A type of virus that infects and lyses (breaks down) cancer cells but not normal cells. Oncolytic viruses can occur naturally or can be made in the laboratory by changing other viruses. Certain oncolytic viruses are being studied in the treatment of cancer. They may make it easier to kill tumor cells with chemotherapy and radiation therapy.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(oncolytic virus) Manipulated or engineered viruses having oncolytic properties to selectively replicate in and kill targeted cancer cells, leaving normal cells unharmed.NCI ThesaurusU.S. National Cancer Institute, 2021
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Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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