Disease or Syndrome
optic atrophy
chi·as·ma at·ro·phy [ op-tik a-truh-fee ]
Subclass of:
Disorder of the optic nerve
Definitions related to optic atrophy:
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A disorder characterized by loss of optic nerve fibers. It may be inherited or acquired. Acquired causes include ischemia, optic nerve neuropathy, glaucoma, trauma, radiation, brain tumors, and multiple sclerosis. It leads to vision disturbances.NCI ThesaurusU.S. National Cancer Institute, 2021
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Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions are relatively common causes of this condition.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Atrophy of the optic nerve. Optic atrophy results from the death of the retinal ganglion cell axons that comprise the optic nerve and manifesting as a pale optic nerve on fundoscopy.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Optic atrophy is the final common morphologic endpoint of any disease process that causes axon degeneration in the retinogeniculate pathway. Clinically, optic atrophy manifests as changes in the color and the structure of the optic disc associated with variable degrees of visual dysfunction.WebMD, 2019
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Optic atrophy, degeneration of the optic nerve (the second cranial nerve) due to direct or indirect damage to a particular type of retinal cell, called ganglion cells, whose axonal projections collectively make up the optic nerve. The function of the optic nerve is to carry visual data from the...Encyclopedia Britannica, Inc., 2020
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