Disease or Syndrome
osteomalacia
os·te·o·ma·la·cia [ os-tee-oh-muh-ley-shuh, -shee-uh, -see-uh ]
Etymology:
Greek osteon = bone + malakia = a softening
Definitions related to osteomalacia:
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A condition in which bones are soft and weak, usually due to a lack of vitamin D or an inability of the body to use vitamin D properly.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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A metabolic bone disease that results from either a deficiency in vitamin D, or an abnormality in the metabolism of vitamin D, or a deficiency of calcium in the diet. The most common symptoms are bone pain and muscle weakness. When it occurs in children it is commonly referred to as rickets. (Diagnostic Surgical Pathology, 3rd ed.) --2003NCI ThesaurusU.S. National Cancer Institute, 2021
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Decreased mineralization of newly formed osteoid at sites of bone turnover in established bone due to deficiency of calcium, phosphate, or vitamin D.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Inadequate or delayed mineralization of osteoid in mature cortical and spongy bone.CRISP ThesaurusNational Institutes of Health, 2006
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Osteomalacia is a general term for bone weakness owing to a defect in mineralization of the protein framework known as osteoid. This defective mineralization is mainly caused by lack in vitamin D. Osteomalacia in children is known as rickets.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Osteomalacia refers to a marked softening of your bones, most often caused by severe vitamin D deficiency. The softened bones of children and young adults with osteomalacia can lead to bowing during growth, especially in weight-bearing bones of the legs. Osteomalacia in older adults can lead to fractures.Mayo Foundation for Medical Education and Research
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Osteomalacia is a disease that is characterized by a weakening of the bone, often due to a deficiency of vitamin D. This vitamin supports the development of the bones of the body, so when there are low levels of vitamin D, the bones are not strong enough. Symptoms of osteomalacia can include muscle weakness, bone pain, and walking with a...National Center for Advancing Translational Sciences
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Osteomalacia is a metabolic bone disease characterized by incomplete mineralization of the underlying mature organic bone matrix (osteoid) following growth plate closure in adults. In contrast, rickets is a metabolic bone disease characterized by defective mineralization of the epiphyseal growth plate cartilage in children, resulting in...Athenahealth, Inc., 2019
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Osteomalacia, condition in which the bones of an adult progressively soften because of inadequate mineralization of the bone. (In children the condition is called rickets.) Osteomalacia may occur after several pregnancies or in old age, resulting in increased susceptibility to fractures. Symptoms...Encyclopedia Britannica, Inc., 2020
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