Immunologic Factor
panitumumab
[ pan-ih-too-myoo-mab ]
Brand Names:
Vectibix
May Treat:
Colorectal Neoplasms
More Information:
Definitions related to panitumumab:
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A human monoclonal antibody produced in transgenic mice that attaches to the transmembrane epidermal growth factor (EGF) receptor. Panitumumab may inhibit autocrine EGF stimulation of tumor cells that express the EGF receptor, thereby inhibiting tumor cell proliferation.NCI ThesaurusU.S. National Cancer Institute, 2021
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A human monoclonal antibody that is being used to treat colorectal cancer that has spread to other parts of the body. It is used in patients whose disease has not gotten better during or after treatment with other anticancer drugs. It is also being studied in the treatment of other types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. ABX-EGF binds to the epidermal growth factor receptor (EGFR) and may block tumor cell growth.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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