Quantitative Concept
penetrance Audio
pen·e·trance [ pen-i-truhns ]
Subclass of:
Mode of inheritance; Phenotype
Definitions related to penetrance:
  • A characteristic of a genotype; it refers to the likelihood that a clinical condition will occur when a particular genotype is present.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • The degree or probability to which a genotype is expressed as a phenotype.
    NCI
    U.S. National Cancer Institute, 2021
  • The percent frequency with which a dominant or homozygous recessive gene or gene combination manifests itself in the phenotype of the carriers. (From Glossary of Genetics, 5th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.