Pharmacologic Substance
phenylacetate
Brand Names:
Ammonul
Definitions related to phenylacetate:
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A drug being studied in the treatment of cancer.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(phenyl acetate) An aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibition, and apoptosis in tumor cells. Implicated mechanisms of action include decreased protein prenylation, activation of the peroxisome proliferation-activated receptors, inhibition of DNA methylation, and depletion of glutamine. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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