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Pharmacologic Substance
phenytoin sodium Audio
phen·y·to·in so·di·um [ feh-nih-toh-in soh-dee-um ]
Effect:
Decreased Disorganized Electrical Activity; Decreased Organized Electrical Activity
May Prevent:
Epilepsy, Post-Traumatic
May Treat:
Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Status Epilepticus
More Information:
ChemID; DailyMed; PDR
Definitions related to phenytoin sodium:
  • A drug used to treat or prevent seizures or convulsions that may be caused by epilepsy, brain surgery, or treatment for brain cancer. It is a type of anticonvulsant agent.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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