Pharmacologic Substance
phenytoin sodium
phen·y·to·in so·di·um [ feh-nih-toh-in soh-dee-um ]
Effect:
Decreased Disorganized Electrical Activity; Decreased Organized Electrical Activity
May Prevent:
Epilepsy, Post-Traumatic
May Treat:
Epilepsy, Temporal Lobe;
Epilepsy, Tonic-Clonic;
Status Epilepticus
More Information:
Definitions related to phenytoin sodium:
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A drug used to treat or prevent seizures or convulsions that may be caused by epilepsy, brain surgery, or treatment for brain cancer. It is a type of anticonvulsant agent.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity.NCI ThesaurusU.S. National Cancer Institute, 2021
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