Pharmacologic Substance
picoplatin
Definitions related to picoplatin:
  • A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.
    NCI
    U.S. National Cancer Institute, 2021
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called platinum analogs.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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