Pharmacologic Substance
piritrexim Audio
[ peer-ee-trek-sim ]
Definitions related to piritrexim:
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called folate antagonists.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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