Neoplastic Process
plasmablastic lymphoma
[ plaz-muh-blas-tik lim-foh-muh ]
Subclass of:
Diffuse Large B-Cell Lymphoma
Definitions related to plasmablastic lymphoma:
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An aggressive diffuse large B-cell lymphoma frequently arising in the setting of HIV infection and characterized by the presence of large neoplastic cells resembling B-immunoblasts which have the immunophenotypic profile of plasma cells. Sites of involvement include the oral cavity, sinonasal cavity, skin, soft tissues, gastrointestinal tract, and bone.NCI ThesaurusU.S. National Cancer Institute, 2021
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Malignant lymphoma composed of large B lymphoid cells which have the immunophenotype of plasma cells and a predilection for the ORAL CAVITY.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Plasmablastic lymphoma is an aggressive form of non-Hodgkin lymphoma. Although the condition most commonly occurs in the oral cavity, it can be diagnosed in many other parts of the body such as the gastrointestinal tract, lymph nodes, and skin. The exact underlying cause of plasmablastic lymphoma is poorly understood; however, it is...National Center for Advancing Translational Sciences
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