Organ or Tissue Function
platelet activation
plate·let ac·tiva·tion [ pleyt-lit ak-tuh-vey-shun ]
Subclass of:
Hemostatic function
Definitions related to platelet activation:
  • A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
    Gene Ontology Dictionary
    Gene Ontology Consortium, 2021
  • A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Platelet Activation involves initiation of a set of stimulated platelet activities involved in aggregation of platelets and fibrin during blood coagulation.
    NCI
    U.S. National Cancer Institute, 2021
  • Process by which platelets change shape, aggregate, adhere to vascular wall, and secrete cytokines during clotting; induced by a variety of agonists including thrombin, ADP, PAF, and epinephrine via a G protein/IP3 coupled receptor system.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.