Pharmacologic Substance
podophyllin
[ pod-uh-fil-in ]
Brand Names:
Podocon
Effect:
Decreased Mitosis
May Treat:
Condylomata Acuminata; Papilloma
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to podophyllin:
  • A resin extracted from the root of the plant Podophyllum sp. Berberidaceae (mandrake), which contains numerous compounds, among which podophyllotoxin is the principal active component. Podophyllin arrests mitosis in metaphase. Podophyllotoxin offers advantages over podophyllin in terms of purity, stability and lack of systemic toxicity. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • Caustic extract from the roots of Podophyllum peltatum and P. emodi. It contains PODOPHYLLOTOXIN and its congeners and is very irritating to mucous membranes and skin. Podophyllin is a violent purgative that may cause CNS damage and teratogenesis. It is used as a paint for warts, skin neoplasms, and senile keratoses.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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