Pharmacologic Substance
poly ICLC
Definitions related to poly iclc:
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(poly-iclc) A substance that is being studied in the treatment of cancer and for its ability to stimulate the immune system. It is made in the laboratory by combining the nucleic acid RNA with the chemicals poly-L-lysine and carboxymethyl cellulose.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. Poly ICLC may stimulate the release of cytotoxic cytokines and, by inducing interferon-gamma production, may increase the tumoricidal activities of various immunohematopoietic cells. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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