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Polycystic Ovarian Syndrome
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Polycystic Ovarian Syndrome
Paul Bolin
Disease or Syndrome
polycystic ovary syndrome Audio
[ pah-lee-sis-tik oh-vuh-ree sin-drome ]
Subclass of:
Ovarian Cysts
Also called:
PCOS; Stein-Leventhal Syndrome; Hyperandrogenic Chronic Anovulation
Definitions related to polycystic ovary syndrome:
  • A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A condition marked by infertility, enlarged ovaries, menstrual problems, high levels of male hormones, excess hair on the face and body, acne, and obesity. Women with PCOS have an increased risk of diabetes, high blood pressure, heart disease, and endometrial cancer.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A condition of unknown or heterogenous genetic etiology that is characterized by hyperandrogenism and ovarian dysfunction, though the clinical features of the condition may differ between teenage girls and adult women. For teenage girls, the characteristic features generally manifest as persistent, otherwise unexplained hyperandrogenism and reduced or absent ovulation with associated menstrual irregularity, as determined by age- and pubertal stage-appropriate criteria. Additional clinical manifestations include some or all of the following: obesity, insulin resistance/hyperinsulinemia or frank type 2 diabetes mellitus, acanthosis nigricans, hirsutism, and polycystic ovary on ultrasound.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity.
    NCI
    U.S. National Cancer Institute, 2021
  • An inherited disorder characterized by the formation of abnormal cysts in enlarged ovaries; a leading cause of female infertility and a common cause of hirsutism.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • Clinical symptom complex characterized by presence of multiple cysts on the ovaries, oligomenorrhea or amenorrhea, anovulation and regularly associated with excessive amounts of body hair (hirsuitism), excessive body weight, infertility and insulin resistance.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Polycystic ovary syndrome (PCOS) is the name for set of symptoms that are related to an imbalance of hormones. PCOS affects the ovaries, as well as many other parts of the body. People with PCOS usually have at least two of these problems: Not ovulating. Normally, your ovaries make the egg that is released each month as part of a healthy menstrual cycle. This is called ovulation. But with PCOS, the egg may not develop as it should, or it may not be released during ovulation. Your periods may be irregular, or you may not have them at all.; High levels of androgens. Androgens are hormones that are important for normal male sexual development. Women normally make smaller amounts of androgens. Having higher levels of androgens can cause you to have extra body or facial hair (called hirsutism).; Cysts in one or both ovaries. Cysts are growths that are small, fluid-filled sacs. The exact cause of PCOS in unknown. Research has shown that different factors may play a role, including: Genetics. PCOS tends to run in families.; Imbalances in androgen levels.; Insulin resistance. This is a condition in which your body can't use insulin properly. Insulin is a hormone that helps move blood glucose (sugar) into your cells to give them energy. Insulin resistance can lead to high blood glucose levels. PCOS often develops as young as age 11 or 12, around the time of your first period. But you can develop it later. The symptoms can vary from person to person. Some people have few or even no symptoms. They may not realize they have PCOS until they have trouble getting pregnant. Other people may have more severe symptoms. The symptoms of PCOS may include: Irregular or missed menstrual periods.; Too much hair on the face, chest, stomach, or thighs.; Obesity, weight gain, or trouble losing weight.; Severe acne which may be hard to treat.; Oily skin.; Patches of thickened dark skin (called acanthosis nigricans).; Infertility. PCOS is one of the most common causes of infertility. But many people with PCOS can still get pregnant. PCOS is linked to many other health problems, including: Insulin resistance, which can lead to prediabetes and type 2 diabetes.; Heart disease. Having PCOS increases your risk, and this risk goes up as you age.; High blood pressure.; High LDL ("bad") cholesterol and low HDL ("good") cholesterol. This increases your risk of heart disease.; Sleep apnea, a disorder that causes you to repeatedly stop breathing during sleep.; Depression and anxiety. Although there are links between PCOS and these conditions, researchers do not know whether: PCOS causes some of these problems; Some of these problems cause PCOS, or; There are other conditions that cause both PCOS and these other health problems. Not everyone who has PCOS will have all these problems. However, you and your health care provider may want to monitor your health for signs of them, so they can be treated early. There is no specific test for PCOS. To find out if you have PCOS, your provider: Will do a physical exam, which will include looking for the physical signs of PCOS.; Will ask about your medical history and family health history.; May do a pelvic exam to check for signs of extra male hormones and to see if your ovaries are enlarged or...
    MedlinePlus
    U.S. National Library of Medicine, 2025
  • Polycystic ovary syndrome (PCOS) is the name for set of symptoms that are related to an imbalance of hormones. PCOS affects the ovaries, as well as many other parts of the body. People with PCOS usually have at least two of these problems: Not ovulating. Normally, your ovaries make the egg that is released each month as part of a healthy menstrual cycle. This is called ovulation. But with PCOS, the egg may not develop as it should, or it may not be released during ovulation. Your periods may be irregular, or you may not have them at all.; High levels of androgens. Androgens are hormones that are important for normal male sexual development. Women normally make smaller amounts of androgens. Having higher levels of androgens can cause you to have extra body or facial hair (called hirsutism).; Cysts in one or both ovaries. Cysts are growths that are small, fluid-filled sacs. The exact cause of PCOS in unknown. Research has shown that different factors may play a role, including: Genetics. PCOS tends to run in families.; Imbalances in androgen levels.; Insulin resistance. This is a condition in which your body can't use insulin properly. Insulin is a hormone that helps move blood glucose (sugar) into your cells to give them energy. Insulin resistance can lead to high blood glucose levels. PCOS often develops as young as age 11 or 12, around the time of your first period. But you can develop it later. The symptoms can vary from person to person. Some people have few or even no symptoms. They may not realize they have PCOS until they have trouble getting pregnant. Other people may have more severe symptoms. The symptoms of PCOS may include: Irregular or missed menstrual periods.; Too much hair on the face, chest, stomach, or thighs.; Obesity, weight gain, or trouble losing weight.; Severe acne which may be hard to treat.; Oily skin.; Patches of thickened dark skin (called acanthosis nigricans).; Infertility. PCOS is one of the most common causes of infertility. But many people with PCOS can still get pregnant. PCOS is linked to many other health problems, including: Insulin resistance, which can lead to prediabetes and type 2 diabetes.; Heart disease. Having PCOS increases your risk, and this risk goes up as you age.; High blood pressure.; High LDL ("bad") cholesterol and low HDL ("good") cholesterol. This increases your risk of heart disease.; Sleep apnea, a disorder that causes you to repeatedly stop breathing during sleep.; Depression and anxiety. Although there are links between PCOS and these conditions, researchers do not know whether: PCOS causes some of these problems; Some of these problems cause PCOS, or; There are other conditions that cause both PCOS and these other health problems. Not everyone who has PCOS will have all these problems. However, you and your health care provider may want to monitor your health for signs of them, so they can be treated early. There is no specific test for PCOS. To find out if you have PCOS, your provider: Will do a physical exam, which will include looking for the physical signs of PCOS.; Will ask about your medical history and family health history.; May do a pelvic exam to check for signs of extra male hormones and to see if your ovaries are enlarged or...
    MedlinePlus Genetics
    U.S. National Library of Medicine, 2021
  • Polycystic ovary syndrome is a clinical syndrome characterized by mild obesity, irregular menses or amenorrhea, and signs of androgen excess (eg, hirsutism, acne). Most patients have multiple cysts in the ovaries. Diagnosis is by pregnancy testing, hormone measurement, and imaging to exclude a virilizing tumor. Treatment is symptomatic.
    Merck Manuals
    Merck & Co., Inc., 2025
  • The major features of polycystic ovarian syndrome (PCOS) include menstrual dysfunction, anovulation, and signs of hyperandrogenism. Although the exact etiopathophysiology of this condition is unclear, PCOS can result from abnormal function of the hypothalamic-pituitary-ovarian (HPO) axis.
    Medscape
    WebMD, 2025
  • Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of reproductive age. Women with PCOS may have infrequent or prolonged menstrual periods or excess male hormone (androgen) levels. The ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Polycystic ovarian syndrome (PCOS) is a health problem that can affect a woman's menstrual cycle, ability to have children, hormones, heart, blood vessels, and appearance. Women with this condition typically have high levels of hormones called androgens, missed or irregular periods, and many small cysts in their ovaries. The cause of...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
  • Polycystic ovary syndrome (PCOS) includes symptoms of hyperandrogenism, presence of hyperandrogenemia, oligo/anovulation, and polycystic ovarian morphology on ultrasound.
    Epocrates
    Athenahealth, Inc., 2019
  • Stein-Leventhal syndrome, disorder in women that is characterized by an elevated level of male hormones (androgens) and infrequent or absent ovulation (anovulation). About 5 percent of women are affected by Stein-Leventhal syndrome, which is responsible for a substantial proportion of cases of...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2025
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