Congenital Abnormality
polymicrogyria
Subclass of:
Malformations of Cortical Development, Group III
Definitions related to polymicrogyria:
  • A developmental brain abnormality characterized by an excessive amount of small convolutions on the surface of the brain and cognitive dysfunction.
    NCI
    U.S. National Cancer Institute, 2021
  • Heterogeneous disorders of cortical malformation characterized by excessive and small fused gyri and shallow sulci of the CORTEX with abnormal cortical lamination. It is considered a malformation secondary to abnormal post-migrational development of the neurons during cerebral cortical development and is associated with EPILEPSY and learning difficulties.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Polymicrogyria is a congenital malformation of the cerebral cortex characterized by abnormal cortical layering (lamination) and an excessive number of small gyri (folds).
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Polymicrogyria is a condition characterized by abnormal development of the brain before birth. Specifically, the surface of the brain develops too many folds which are unusually small. The signs and symptoms associated with the condition vary based on how much of the brain and which areas of the brain are affected; however, affected...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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