Biologically Active Substance
pre-miRNA
Definitions related to pre-mirna:
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Precursors to miRNA generated from pri-miRNA. They are exported from the nucleus where they are further processed by Dicer RNase to generate mature miRNA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The pre-miRNA is an oligoribonucleotide intermediate of nuclear transcription that is further processed cytosolically by the Dicer enzyme to form 20-25 nt mature miRNA products. Such RNA intermediates, typically 65-110 nt in length, form stem-loop structures that play an important role in the processing of these oligonucleotides to the mature miRNA form.NCI ThesaurusU.S. National Cancer Institute, 2021
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