Neoplastic Process
prolactinoma
Subclass of:
Pituitary Neoplasms;
Adenoma
Definitions related to prolactinoma:
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A benign tumor (adenoma) of the pituitary gland.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A non-malignant prolactin-secreting pituitary tumor.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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AIP familial isolated pituitary adenoma (AIP-FIPA) is defined as the presence of an AIP germline pathogenic variant in an individual with a pituitary adenoma (regardless of family history). The most commonly occurring pituitary adenomas in this disorder are growth hormone-secreting adenomas (somatotropinoma), followed by prolactin-secreting adenomas (prolactinoma), growth hormone and prolactin co-secreting adenomas (somatomammotropinoma), and nonfunctioning pituitary adenomas (NFPA). Rarely TSH-secreting adenomas (thyrotropinomas) are observed. Clinical findings result from excess hormone secretion, lack of hormone secretion, and/or mass effects (e.g., headaches, visual field loss). Within the same family, pituitary adenomas can be of the same or different type. Age of onset in AIP-FIPA is usually in the second or third decade.GeneReviewsUniversity of Washington, 2021
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(lactotroph adenoma) An adenoma of the anterior lobe of the pituitary gland that produces prolactin. It is the most common type of pituitary gland adenomas and it is associated with hyperprolactinemia. Clinical manifestations include amenorrhea, galactorrhea, impotence, headache, and visual disturbances.NCI ThesaurusU.S. National Cancer Institute, 2021
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(pituitary prolactin cell adenoma) A type of pituitary adenoma originating in prolactin secreting cells. This kind of adenoma is characterized by overproduction of prolactin, and may cause loss of menstrual periods and breast milk production in women.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Prolactinomas are the most common hormone-secreting pituitary tumors. Based on its size, a prolactinoma can be classified as a microprolactinoma (< 10 mm diameter) or a macroprolactinoma (>10 mm diameter).WebMD, 2019
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Prolactinoma is a noncancerous tumor of the pituitary gland. This tumor causes the pituitary to make too much of a hormone called prolactin. The major effect of prolactinoma is decreased levels of some sex hormones - estrogen in women and testosterone in men.Mayo Foundation for Medical Education and Research
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Prolactinoma is a tumor of the pituitary gland that causes increased levels of the hormone prolactin. This hormone normally stimulates breast development and milk production in women. Prolactinoma can affect men or women. In women, the symptoms may include unusual milk production (galactorrhea) when not pregnant or nursing and having no...National Center for Advancing Translational Sciences
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Prolactinomas are benign lactotroph adenomas expressing and secreting prolactin.Athenahealth, Inc., 2019
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