Molecular Function
protein denaturation
Subclass of:
Protein Unfolding
Definitions related to protein denaturation:
-
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
Process of unfolding or otherwise grossly changing the tertiary structure of a protein; usually applies to experimental treatments, although may occur in biological contexts (e.g., "heat shock").CRISP ThesaurusNational Institutes of Health, 2006
-
Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.Gene Ontology DictionaryGene Ontology Consortium, 2021
Return to OpenMD Medical Dictionary
> P
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.