Laboratory Procedure
prothrombin time
pro·throm·bin time [ proh-throm-bin tahym ]
Subclass of:
Blood Physiological Phenomena;
Blood coagulation tests
Definitions related to prothrombin time assay:
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(prothrombin time) A blood clotting measurement that evaluates the extrinsic pathway of coagulation.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(prothrombin time) A measurement of the clotting time of plasma recalcified in the presence of excess tissue thromboplastin; it is a measure of the extrinsic pathway of coagulation. It is used to determine the clotting tendency of blood, in the measure of warfarin dosage, liver damage and vitamin K status. Factors measured are fibrinogen, prothrombin, and factors V, VII, and X.NCI ThesaurusU.S. National Cancer Institute, 2021
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(prothrombin time) Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. Factors measured are FIBRINOGEN; PROTHROMBIN; FACTOR V; FACTOR VII; and FACTOR X. It is used for monitoring anticoagulant therapy with COUMARINS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A basic understanding of the coagulation pathway is required to interpret prothrombin time result (see the image below). The prothrombin time is a measure of the integrity of the extrinsic and final common pathways of the coagulation cascade.WebMD, 2019
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