Cell or Molecular Dysfunction
retrograde degeneration
ret·ro·grade de·gen·er·a·tion
Subclass of:
Nerve Degeneration
Definitions related to retrograde degeneration:
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(axon reaction) Series of changes in the ganglion cell following the severing of its axon.CRISP ThesaurusNational Institutes of Health, 2006
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Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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